Dec 27, 2005 · Together these data led us to hypothesize that neurons in the superficial layers of the adult cortex can undergo arbor remodeling without extreme peripheral perturbation. To test this hypothesis, we imaged the dendritic arbors of neurons in the visual cortex of Cited by: 241. Visual area V2, or secondary visual cortex, also called prestriate cortex, is the second major area in the visual cortex, and the first region within the visual association area. It receives strong feedforward connections from V1 (direct and via the pulvinar) and sends strong connections to V3, V4, and V5.FMA: 242644.
Aug 22, 2017 · Augmentation of Arc Expression in Adult Mouse Visual Cortex Extends the Critical Period of Juvenile OD Plasticity. In young mice [≤ postnatal day (P) 40], the main consequence of short (3–4 d) MD is the robust loss of cortical responsiveness to stimulation of the deprived eye.Cited by: 10. May 20, 2015 · The maturation of inhibitory circuits in the juvenile cortex triggers a critical period of plasticity in visual system development. Although several manipulations of inhibition can alter its timing, none have reactivated critical period plasticity in adulthood. We developed a transplantation method Cited by: 67.
The synaptic and circuit mechanisms underlying such plasticity are being progressively understood. Increasing evidence supports the hypothesis that plasticity in both the developing and adult visual cortex is initiated by a transient reduction of inhibitory drive, and implemented by persistent changes at excitatory synapses. Apr 18, 2008 · We investigated whether fluoxetine, a widely prescribed medication for treatment of depression, restores neuronal plasticity in the adult visual system of the rat. We found that chronic administration of fluoxetine reinstates ocular dominance plasticity in adulthood and promotes the recovery of visual functions in adult amblyopic animals, as tested electrophysiologically and behaviorally.Cited by: 695.